2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

Related Products

PDF 32.36 MB

Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-105138
    (6R)-Naxifylline 166374-48-7 98%
    (6R)-Naxifylline ((6R)-BG9719) (ENX R-enantiomer) is the R-enantiomer of Naxifylline (HY-19240). (6R)-Naxifylline is a A1-adenosine antagonist with saluretic activity. (6R)-Naxifylline induces relaxation of spontaneous tone in guinea pig trachea.
    (6R)-Naxifylline
  • HY-105168
    TAK 044 157380-72-8 98%
    TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage.
    TAK 044
  • HY-105205
    Terlakiren 119625-78-4 98%
    Terlakiren (CP-80,794) is an orally active inhibitor of renin. Terlakiren inhibits the efficacy of human renin with an IC50 value of 0.7 nM. Terlakiren has potential applications in hypertension.
    Terlakiren
  • HY-105240
    Delparantag 872454-31-4 98%
    Delparantag (PMX-60056) is a salicylamide derivative and an effective unfractionated heparin (UFH) and low molecular weight heparin (LMWH) reversing agent. Delparantag shows ability to neutralize the anticoagulation and bleeding effects of UFH and LMWH.
    Delparantag
  • HY-105266
    Zabicipril 83059-56-7 98%
    Zabicipril is an orally active angiotensin-converting enzyme (ACE) inhibitor. Zabicipril can be used for the study of blood pressure and peripheral arterial insufficiency.
    Zabicipril
  • HY-105323
    YM758 phosphate 312752-86-6 98%
    YM758 phosphate is a "funny" If current channel (If channel) inhibitor.
    YM758 phosphate
  • HY-105440
    LY 301875 154668-27-6 98%
    LY 301875 is a potent and orally active angiotensin II receptor type 1 (AT1) antagonist with a pKB value of 9.6.
    LY 301875
  • HY-105495
    Iliparcil 137214-72-3 98%
    Iliparcil has a potent antithrombotic activity in the Wessler model in rats. Iliparcil has oral activity.
    Iliparcil
  • HY-105562
    Nadoxolol 54063-51-3 98%
    Nadoxolol is a non-selective β-adrenaline receptor blocker that can be used in the study of arrhythmias. .
    Nadoxolol
  • HY-105572
    Moveltipril calcium 85921-53-5 98%
    Moveltipril calcium (MC-838 calcium) is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moveltipril calcium binds via a stable thioester bond and exhibits relative resistance to enzymatic hydrolysis in rat liver homogenate. Moveltipril calcium effectively inhibits ACE extracted from rabbit lung in a concentration-dependent manner. Moveltipril calcium is able to highly specifically inhibit the contractile response to angiotensin-I (AI) in free rat aortic rings and guinea pig ileum preparations, while enhancing the contractile response to calcitonin.
    Moveltipril calcium
  • HY-105647
    Ambuphylline 5634-34-4 98%
    Ambuphylline (Bufylline) is a bronchodilator. Ambuphylline is a theophylline derivative possibly acting through phosphodiesterase inhibition. Ambuphylline can be used for the research of asthma and other lung diseases.
    Ambuphylline
  • HY-10564S
    Sarpogrelate-d3 hydrochloride 98%
    Sarpogrelate-d3 (hydrochloride) is the deuterium labeled Sarpogrelate hydrochloride. Sarpogrelate hydrochloride (MCI-9042) is a selective 5-HT2R antagonist, with pKis of 8.52, 6.57, and 7.43 for 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively. Sarpogrelate hydrochloride displays selectivity over 5-HT1, 5-HT3, 5-HT4, α1-, α2- and β-adrenoreceptor, histamine H1, H2 and muscarinic M3 receptors. Sarpogrelate hydrochloride can be used for the research of vascular disease associated with thrombosis.
    Sarpogrelate-d3 hydrochloride
  • HY-105651
    Butalamine 22131-35-7 98%
    Butalamine is a vasodilator.
    Butalamine
  • HY-105666
    TGX-155 351071-90-4 98%
    TGX-155 (AZ12649385) is a selective inhibitor of PI3Kβ. TGX-155 has potential applications in antithrombotic therapy.
    TGX-155
  • HY-105686
    FR-229934 799841-02-4 98.65%
    FR-229934 is a PDE V inhibitor extracted from patent WO2019130052A1. FR-229934 can be used for the research of pulmonary arterial hypertension and erectile dysfunction.
    FR-229934
  • HY-105697
    Protoveratrine A 143-57-7 98%
    Protoveratrine A (NSC 7526; Protalba; Protoveratrin) is an alkaloid with strong cardiostimulant and vasoconstrictive effects, which can be used in the study of hypertension and other cardiovascular diseases.
    Protoveratrine A
  • HY-105698
    Clofexamide 1223-36-5 98%
    Clofexamide (ANP 246; Amichlophene) is a potent antidepressant agent. Clofexamide also shows anti-inflammatory activity.
    Clofexamide
  • HY-105718
    Olmidine 31105-14-3 98%
    Olmidine (DL-Olmidine) is an antihypertensive agent. Olmidine acts through inhibition of the adrenergic transmission.
    Olmidine
  • HY-105790
    Piperilate 4546-39-8 98%
    Piperilate (Pipethanate) is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate also causes hypotension and rescues mice poisoned by the organophosphates.
    Piperilate
  • HY-105829
    Sulfatroxazole 23256-23-7 98%
    Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of ETA receptor (IC50=0.26 μM).
    Sulfatroxazole
Cat. No. Product Name / Synonyms Application Reactivity